1. Open Access Kent State
  2. Comparative Spectrophotometrc Analysis of Rifampicin by Chelate Formation and Charge-Transfer Complexation
Author(s)
Abstract

Simple, rapid, and accurate spectrophotometrc procedures for the determination of the antibiotic rifampicin, in capsules, are presented. A chelate formation of the antibiotic with cupric ion and charge-transfer complexation with halogenated quinones are carried out. Linear correlations between absorbance and concentration over the range of 40-100 μg ml−1 were computed. The reaction pathways were proposed. The utility of copper chelate as a stability indicating procedure as well as a method to determine rifampicin In spiked urine samples is demonstrated.
Format
Article
Identifier(s)
10.1080/00032719208020030
Publication Date
1992-04-01
Publication Title
Analytical Letters
Volume
25
Issue
4
First Page
725
Last Page
743
Keywords
Subject
Rights
http://rightsstatements.org/vocab/InC/1.0/
Community
Department of Chemistry & Biochemistry
Permalink https://oaks.kent.edu/chempubs/37
Galal, S., Blaih, S., & Abdel-Hamid, M. (1992). Comparative Spectrophotometrc Analysis of Rifampicin by Chelate Formation and Charge-Transfer Complexation (1–). Analytical Letters. https://doi.org/10.1080/00032719208020030
Galal, Shereen, Salah Blaih, and Mohamed Abdel-Hamid. 1992. “Comparative Spectrophotometrc Analysis of Rifampicin by Chelate Formation and Charge-Transfer Complexation”. Analytical Letters. https://doi.org/10.1080/00032719208020030.
Galal, Shereen, et al. Comparative Spectrophotometrc Analysis of Rifampicin by Chelate Formation and Charge-Transfer Complexation. Analytical Letters, 1 Apr. 1992, https://doi.org/10.1080/00032719208020030.