Title

Spectrophotometric Determination of Enalapril Maleate and Ramipril in Dosage Forms

Publication Title

Spectroscopy Letters

Publication Date

6-20-1999

Document Type

Article

DOI

http://dx.doi.org/10.1080/00387010009350061

Keywords

enalapril maleate, ramipril, p-chloranilic acid, picric acid, bromocresol green, dosage forms

Disciplines

Chemicals and Drugs | Chemistry | Medicinal and Pharmaceutical Chemistry

Abstract

Three sensitive and accurate spectrophotometric methods have been developed for the assay of enalapril maleate and ramipril, each in its dosage forms. These methods depend on the reaction of the drugs with p-chloranilic acid, the reaction with picric acid, and the ion-pair salt formation with bromocresol green. The proposed methods have been applied to the analysis of these drugs in their commercial tablets. The results obtained were precise and accurate.

Publisher

Taylor & Francis Group


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