Abstract

Staphylococcus Aureus is currently one of the leading causes of infections in diabetic patients and a major cause of chronic wounds. Staphylococcus Aureus is also a common nosocomial infection as it is an opportunistic pathogen that can live in the epidermis of around 30% of the population. The infection can persist easily and become resistant to antibiotics through the formation of biofilms which can quickly aggregate other Staphylococcus Aureus cells. With need for treatment of these infections on the rise, more research needs to be conducted on the effects of antibiotics on the S. Aureus biofilms. This study will compare the effects of Vancomycin and Ciproflaxin on both planktonic and biofilm S. Aureus to determine the minimum inhibitory concentration of the planktonic bacteria (MIC), the minimum biofilm inhibitory concentration (MBIC), and the minimum biofilm eradication concentration (MBEC). The MBIC and MBEC will be compared with the MIC to measure the effects of biofilms on the antimicrobial susceptibility patterns of S. Aureus.

Modified Abstract

Staphylococcus Aureus is currently one of the leading causes of infections in diabetic patients and a major cause of chronic wounds. Staphylococcus Aureus is also a common nosocomial infection as it is an opportunistic pathogen that can live in the epidermis of around 30% of the population. The infection can persist easily and become resistant to antibiotics through the formation of biofilms which can quickly aggregate other Staphylococcus Aureus cells. With need for treatment of these infections on the rise, more research needs to be conducted on the effects of antibiotics on the S. Aureus biofilms.

Research Category

Biomedical Sciences

Primary Author's Major

Biotechnology

Mentor #1 Information

Dr. Min-Ho Kim

Presentation Format

Poster

Start Date

21-3-2017 1:00 PM

Research Area

Bacteria | Bacterial Infections and Mycoses | Medical Biotechnology | Medical Immunology | Medical Molecular Biology

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Mar 21st, 1:00 PM

Antimicrobial Susceptibility Patterns of S. Aureus Biofilms

Staphylococcus Aureus is currently one of the leading causes of infections in diabetic patients and a major cause of chronic wounds. Staphylococcus Aureus is also a common nosocomial infection as it is an opportunistic pathogen that can live in the epidermis of around 30% of the population. The infection can persist easily and become resistant to antibiotics through the formation of biofilms which can quickly aggregate other Staphylococcus Aureus cells. With need for treatment of these infections on the rise, more research needs to be conducted on the effects of antibiotics on the S. Aureus biofilms. This study will compare the effects of Vancomycin and Ciproflaxin on both planktonic and biofilm S. Aureus to determine the minimum inhibitory concentration of the planktonic bacteria (MIC), the minimum biofilm inhibitory concentration (MBIC), and the minimum biofilm eradication concentration (MBEC). The MBIC and MBEC will be compared with the MIC to measure the effects of biofilms on the antimicrobial susceptibility patterns of S. Aureus.